I'm currently using a dual-core 90 MHz processor that is relatively advanced and has good performance for many applications. It has error-correcting memories (SDRAM, cache, registers) and a lot of integrated peripherals (spacewire, serial, ethernet, 1553, CCSDS) that help reduce board complexity.
Next up in the pipeline is an 8-core 1 GHz monster: https://www.gaisler.com/index.php/products/components/gr765