Mostly yes: I use JS-blocking browser extensions, which (mostly) offer domain-by-domain control over JS loading. And only enable JS when the risk/reward ratio seems low enough.
Between the browser security issues & resource usage, anti-improved speed & UX, etc. - enabling JS is mostly not worth it to me.
(Yes, doing this kinda rules out a fair number of web sites for me. But with ~10,000x more content on the web than I could view in my remaining mortal years anyway...ruling out a lot of sites is a feature, not a bug.)