I would think so. I've lived right next to the Bay Bridge on 2nd St in SF and the amount of soot on my window sills and just inside my windows was a constant chore to clean up. At one point I found a map that stated I lived in the worst place for pollution in SF. I'm much happier now on the west side of the City.
Here's a different SF map showing where most of the exhaust is (PDF): https://www.sfdph.org/dph/files/ehsdocs/airquality/airpollut...