See this diagram on wikipedia for LSD binding affinities (lower means more affinity): https://en.wikipedia.org/wiki/Lysergic_acid_diethylamide#/me...
Biology is extremely complex, and even drugs that have similar receptor binding profiles can have very different effects.
Most drugs will have action across a wide range of receptors. There are a multitude of drugs that target the 5-HT2A receptor, including the most common antidepressants and antipsychotics, for example.
So USB hard drives might be keyboard like (for USB keyboards), but hard drives which dock to the SATA connector aren't …
Anyway, such comparisons sometimes limp and sometimes don't have any legs at all.
Yes alluding to something illegal makes it clickbaity.