For many people it's traditionally Sunday or Saturday, but even if you don't observe a day of rest religiously, it is still very practical. If you are involved with intellectual work like coding, switching your brain to just relax and enjoy life at least one day a week will refresh your focus and drive.
Alan Perlis said to understand a program you must become both the machine and the program, and he also admits that programming is an unnatural act. Programming is essentially forcing your mind to think like a machine, and you can't do this all the time or it will burn you out.
Don't neglect your mental wellbeing, take care of yourself! If you want to be productive, this will help you in the long run. The servers will keep running if you take a bit of time off, people aren't built for 24/7 uptime.