DANE means you get a real PKI with real name constraints, unlike WebPKI.
DANE stapling can reduce latency, but doing DANE w/ qname minimization for most of the domainname being resolved has the property that you get to make life really hard for a malicious or compromised . or TLD. You get to cache a lot of results, so using DANE stapling for the stem of the domainname should still reduce latency a fair bit.
With DNS over TLS or HTTPS we're seeing that resolvers are willing to use TCP, which is one answer to the DNS amplification attack concern.