Is there any reason to think she's about to leave or is this some wishful thinking from the usual suspects?
One of the procedures by which she can be replaced involves 'letters of no confidence' being sent to the '1922 committee'. There are a bunch of newspaper articles saying that committee has been having discreet meetings and talking to Truss yesterday.
Which is the political equivalent of getting invited to a same-day meeting with your boss and HR entitled 'private meeting'.
She's had a terrible week (and that's saying something given her premiership to date).
She had to sack the chancellor that enacted all of her campaign promises, bring in a new chancellor who has undone all of her campaign promises.
Some of the polls coming out suggest the Conservatives would be in 3rd place at a General Election behind the SNP.