There's various levels of foot-gun clicks that can generate AWS bills many orders of magnitude larger.
Reserved Instances are a really quick and easy way to blow a few million with one click.
Europe (Frankfurt), 3 year, all-upfront, Windows w/ SQL Enterprise, Dedicated Tenancy, u-12tb1.112xlarge instance at $5,926,378 up-front.
The discounted $225/hour rate for it disappears into the background noise.
(No, I'm not willing to test it to find out if it actually works)
[1] https://aws.amazon.com/ec2/pricing/reserved-instances/pricin...