I can sustain this claim. I work with a system implemented almost entirely in Oracle PL/SQL. Some tables in the system are nearing 800-900 columns, their size often exceeds 600 GB per table (not many of such large tables though). Querying isn't a problem at all. Large schema changes are also mostly painless. The only point at which one has to be really careful is when a schema change requires actual calculations based on historic data with an additional write on each record.