For my daily browsing I use Firefox with an Extension called Sidebery (https://addons.mozilla.org/en-US/firefox/addon/sidebery/). The ability to logically sort tabs (by default by the tab they were opened from) makes it much much easier dealing with a lot of tabs.

My primary (but not only) use case is researching something and opening every relevant-seeming result in a new tab, afterwards closing the ones that seem the least relevant and keeping the still-open ones around for reference. Then when I'm doing something else (in which the open tabs aren't immediately relevant anymore, but may become so at any time), I can collapse the tree and focus on whatever else I'm doing. Should I then decide that sub-tree isn't relevant anymore, I can close all of the contained tabs at once.

I can't really work with a browser that doesn't have this now. It's so convenient and natural.