I believe that only happens when a Linux package manager updates Firefox while it's running.
Clicking it causes the browser to disappear for ~20 seconds, +10s for the UI to become available.
(It does cause some tabs to message that a browser restart is required. Even so … this is really the first I hit this, as I'm usually doing updates when it is opportunistic to do so, such as right before a reboot (so any kernel updates happen).)