Fly into New York City. Visit museums there for several days. See a Broadway show. See the Intrepid.
Take the train down to Washington DC. Several days at the Smithsonian there, including a trip out to the Udvar-Hazy Center. Take a day trip by train to Baltimore to see the National Aquarium and the Maryland Science Center.
Rent a car, drive to a beach town in Virginia for a weekend; drive back and take the train back to NYC. Or, drive up to a Delaware beach instead and return the car in NYC.
See the other museums in NYC that you missed the first time. Fly home.
E.g. Natural History, Air & Space, etc.
Growing up in the DC area has spoiled me for museums. They're high quality and generally free admission.
Second this. Glad to see that it's still open. I was last there sometime in the early 90's.