We already have many industrial disasters with dangers that need to be communicated to every human generation to come in the form of acid mine drainage and whatnot. Those releases (which would happen absent human upkeep of dams and tailings ponds) are also things that would absolutely wreck environments for hundreds to thousands of years if released.
Every mine you open has clean-up costs that never end; it would be wiser to minimize the amount of new ones. You'll need more of them if you go with the intermittent sources of power because renewables are far more wasteful in terms of materials required (and because they inherently don't produce power constantly).