With a character like Case, you'd need to nail the frenetic energy, like on his last bit of money, strung out, no sleep, basically like a Safdie brothers protagonist. My dream aesthetic would be Safdie brothers + Ridley Scott with a dose of Jóhann Jóhannsson (RIP) for music.
Molly could be interesting if you embrace the street samurai moniker and give her a sort of Yojimbo-esque amusement.
This is a big big change but I'd love it if the Japanese obsession was replaced with a more modern multi-Asian aesthetic. It'd be interesting to blend k-pop and Chinese social media culture into the mix. And make some of the characters Asian-American.