I don't think this is how margin calls work. Presuming your broker is properly managing risk, then a margin call is explicitly designed to not wipe you out financially. You have to put up more capital or sell positions in order to maintain a certain amount of equity in your account, and that required amount is never zero (again, if your broker/lender is managing risk properly).
Of course it is a stressful situation, and he may need to sell assets at "unfavorable" prices which would effectively lock-in some reduced paper wealth. But I don't think a margin call is going to wipe him out.