I'm reminded of this confrontational interaction between a technical person and Steve Jobs: https://www.youtube.com/watch?v=oeqPrUmVz-o -- in hindsight, Jobs was right: "You've got to start with the customer experience and work backwards to the technology," not the other way around.
In Twitter's case, they've got to start with what's important -- being able to try out a lot of new ideas quickly and cheaply to find out which ones work. The exact details of how they accomplish that are of secondary importance.