How is the pathogen still a mystery?
This has been a big problem with chronic illnesses. Even now despite the US military having great indicative data that EBV causes MS there hasn't been much luck in finding the virus in sufferers bodies, just the antibodies and the usual profile of cytokines associated with the viruses presence. Only recently Dr Bhupesh Prusty found EVB and HHV6 in the autopsy of 3 ME/CFS patients brains and none in controls strongly suggesting a viral cause for the disease but its not a test we could do on a live person and they never found these viruses in the patients fluids when they were alive.