I largely use EN for the GTD system. The first GTD step is just capturing info. EN still does this better than any other tool.
EN used to be better at managing large data - but the last major release broke all that. For some reason they favored the new user over the power user.
Some of the things I used to use EN for are now baked into the OS. For instance, the latest release of MacOS now has text search on images. The rise of icloud also got rid of many of my use cases.
What I am doing now is putting files in files and notes in notes. I am converting some notes to files.
I took to heart the scalability issues in EN, and decided to run several note taking apps in parallel. After a while I will just pick a winner.
Sadly - I have not found a replacement for data capture. EN seems to be the only tool that converts email to a note. I might keep the free version of EN around for this task, but I am still looking for a replacement.