The closest thing to acarbose would be a metformin analog berberine, but it doesn't have the gut microbiota remodeling benefits. In terms of rapamycin, it's probably not a supplement but multiday fasting.
That's doable. I already use Berberine, 1.5G/day and I do prolonged fasting but I've not been consistent about doing 5day-FMD, so it seems that is something I need to fix. Thanks for the reply!