yes! In my state, there are dozens of small former industrial towns, often in beautiful natural settings, and/or on excellent transport arteries.

They have space convertible to offices aplenty, revitalizable downtowns, cheap housing. I myself just made the move from the bustling capital city to a wonderful city of 17,000. I bought a large Victorian house for half of what my tiny city house was worth. I can walk to the library, movie theatre, restaurants, cafes. Nature is all around. There is an Amtrak Station. I could go on!

Or.. Remote work will change how we use cities.