I particularly like the 120 orders of magnitude difference in vacuum energy calculations: https://wikenigma.org.uk/content/physics/quantum_physics/vac...
> According to calculations that take into account the Cosmological Constant, the energy should be around 10^−9 joules per cubic meter.
> If on the other hand the calculation is based around Quantum Electrodynamic theory and the Planck Constant, the figure is 10^113 joules per cubic meter.
> One (or both) of the calculations must be wrong - with an error margin of more than 120 orders of magnitude - making it the most spectacular mathematical disagreement in all of physics.