> How much of it was actually the lifestyle changes? It would be more interesting if there were no lifestyle changes...

The article answers this further down:

> Those receiving weekly injections of semaglutide lost, on average, 14.9% of their body weight after 16 months of treatment; those who received a placebo lost 2.4% on average.

Per the article still a lot of work to do in this area, but on the face of it this could be an alternative to bariatric surgery for 1/3 of people.