Interstellar travel is downright easy on time scales of hundred to thousands of years. We just need to make humans last long enough.
This^ is from the traveller's standpoint. I am not completely sure about how long it would take from the perspective of someone on Earth. But this definitely seems plausible if we can solve the other problems with constant acceleration such as sufficient fuel and protection from interstellar dust (at close to light speed, dust would hit with unimaginable force).
[1] https://space.stackexchange.com/questions/840/how-fast-will-...