The problem with this talk is that it's almost content free. He has demonstrated that sometimes we (and other animals) misperceive things, or construct in our heads what we expect to see. He has demonstrated via simple virtual world models that simple artificial organisms evolve to perceive things that keep us alive and ignore other things. But what he has failed to do is tell us anything at all about how our perceptions generally differ from reality. Yes, the map is not the territory - we know that. Yes, we can't directly see atoms, we know that too, though we can with our machines. But other than being a low definition representation, he has not shown any important way in which the map differs from a low definition representation of reality, except that sometimes we make mistakes. He could be right, spacetime could just be the API, but he has presented no evidence for that.