No, I think you've got that backwards. It's other pollutants that may (but also may not) go hand in hand with CO2.
CO2 is the only pollutant constantly produced by people and that works as the main indicator of air quality.
Things like PM2.5 or VOC levels, if they are being produced at all, will also be trapped in stale air. But my apartment, for example, generates virtually none of those, except for when I'm cooking, when it generates massive quantities of PM2.5.
I use a CO2 monitor in my living room and I adjust the crack in the window several times a day to keep it around 550 without wasting too much on heating. It's not even remotely common sense, you absolutely need a sensor.