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(Neptyne cofounder here)

All great tools to be sure! I am a huge fan of numpy and pandas especially. For plotting in Neptyne I usually opt for plotly over matplotlib/seaborn. Agreed too on the shell -- that's why we built one into our product.

I am curious though, do you typically share/collaborate on these spreadsheets with others? Do you have a neat way of packaging up the spreadsheet+Python code?

Somewhat same, but I'm not sure what you need Calc for, I can't remember the last time I deliberately opened a spreadsheet.

On the other hand, while Matplotlib and its ecosystem of add-ons and close imitators is fantastic, it's not friendly to most people, and making it interactive is a massive pain. If you want to wiggle sliders and watch your charts change in real time, you need to use pyplot or something instead.

And it's something that'll literally last forever. Not dependent on a company or pricing.