I have a similar build but using this 2U case that puts all the ports/cards in the front: https://www.amazon.com/gp/product/B01LX0SO53/
I run proxmox, opnsense (virtualized) and other workloads on it. It's really good and runs almost completely silent because of the Noctua fans.
The build quality of the case is lower end though with sharp edges!