> Vinyl chloride is a mutagen having clastogenic effects which affect lymphocyte chromosomal structure.[20][22] Vinyl chloride is a Group 1 human carcinogen posing elevated risks of rare angiosarcoma, brain and lung tumors, and malignant haematopoeitic lymphatic tumors.[23] Chronic exposure leads to common forms of respiratory failure (emphysema, pulmonary fibrosis) and focused hepatotoxicity (hepatomegaly, hepatic fibrosis). Continuous exposure can cause CNS depression including euphoria and disorientation. Decreased male libido, miscarriage, and birth defects are known major reproductive defects associated with vinyl chloride.