I suspect that (some types of) plastics are going to be a big contributer to some of these problems. They contain a number of endocrine disrupting chemicals, and we're typing on them, mousing with them, steering our cars with them, walking on them (most carpet is plastic these days), wearing them, eating off them, drinking from them, washing outselves with them ...

But yeah, the time-lag is a real problem, and coupled with lack of regulation with these technologies and novel compounds that are often introduced into our lives with little or no testing. Very much a "better to seek forgiveness than seek permission" scenario, except in an irresponsible and reckless way that's focused on profit, not safety.