Python can be fast as long as you think in terms of "low level doesn't exist, if I'm looping over items myself there's a problem", right up until you have a problem that can't be expressed in terms of very high level blocks.
I suspect they will be faster than other compiled languages though. The safety will make people less afraid to optimize, in C it's pretty much keep it simple or you're screwed, rust actually helps manage complexity instead of seeming to declaring complexity as not a well supported use case.