I hadn't heard the term CAFO before. Here's a fact sheet from the Sierra Club about these "Concentrated Animal Feeding Operations": https://www.sierraclub.org/michigan/why-are-cafos-bad

I've done a lot of highway driving around the US and CAFOs are probably the worst part of it. They are depressing to look at, and you can often smell them miles before you see them. Central California, all of Nebraska, and Northern Indiana are three places that stand out in my mind for having outrageous "density" of abhorrent-smelling places.