While not a guitar effects box another project that does low latency audio things with an RPI at it’s core: https://monome.org/docs/norns/
Open source version: https://monome.org/docs/norns/shield/
Open source version: https://monome.org/docs/norns/shield/
It has audio in so needs no external usb sound hardware.
It also has a programmable button. A simple idea but very useful
This is the thing that bums me out with DIY audio: people come up with extraordinary designs, do a limited run and then never (or rarely) make any more.
I never bought a milkymist. There are no more being produced. The design has never been updated for modern formats, such as hdmi. I have no clue how to design hardware.
If you ship parts, you can avoid it. If you ship it assembled, you'll need to spend tens of thousands of dollars getting it FCC certified.