>It always confuses me how on a site for techies, where people constantly reason about with virtual concepts and abstractions, the idea that physical biology genes and hormones might be typically but not EXCLUSIVELY coupled with mental sentience is so difficult to imagine.

I personally struggle to understand why a site full of techies can't see the human body for what it is, a genuine masterpiece of engineering with the clear and unmistakable hallmarks of purpose and higher order systems design.

Which, in our experience as engineers, is only ever the product of deliberate intelligence and any claim of exception should really raise eyebrows. Anyone who builds anything should have no trouble with this.

Based on that, I don't believe that the human body was designed for gender fluidity, in fact it is clearly deliberately set up to be binary. Any deviation from that default, in human beings, is unintended error. Perhaps due to deleterious genetic mutation or other entropic effects normally seen in complex systems.

Regardless of what you believe though, the safest thing to say is that we don't fully understand the systems in the body yet, and so Chesterton's Fence should apply. And ESPECIALLY so, when it's deciding whether to perform irreversible surgical work on a vulnerable population.