So if I'm reading this right, 65B at 4bit would consume around 20GB of VRAM and ~130GB of system RAM?
It requires some very minimal system RAM to load the model into VRAM and to compile the 4bit quantized weights.
But if you use pre-quantized weights (get them from HuggingFace or a friend) then all you really need is ~32GB of VRAM and maybe around 2GB of system RAM for 65B. (It's 30B which needs 20GB of VRAM.)
I would not personally call compilation of software part of its "use case." It's use case is text generation.
Or it is probably possible to make it work slowly using a swapfile on Linux.