What is the HEPA for? Is it on the fresh air intake or are you actually HEPA-filtering the recirculated air? If the latter, why not MERV 16? HEPA media is probably more expensive, and it definitely has much higher pressure loss, and there is no actual need for it outside of healthcare.
How are you humidifying?
Can you control the coil temperature in cooling mode and thus control the sensible/latent cooling ratio? (i.e. can the amount of dehumidification be adjusted on the fly as needed?)
Can you integrate with some kind of HRV or ERV?