I would prefer that audio require explicit opt-in, not just interaction. The biggest offender I regularly encounter is not even what I would normally consider an evil website: npr.org
Essentially it's disabling gesture activation, so if you want to allow audio you need to do this explicitly. Note however, that whenever you directly visit a video file, audio will still play but this is very rarely the case.
This is my preferred interface for NPR news, and it might address your issue also: