It is gendered, which I suppose some people take issue with?
Well before the whole shift in language thats going on.
Even manufacturers like MSI for example use the term "Mainboard" in German [1] but "motherboard" in English [2]
[1]: https://de.msi.com/Motherboards/ [2]: https://us.msi.com/Motherboards/
Often used for appliances like washing machine and TVs.
I have a tinkerer friend who call laptop motherboards 'mainboard' to differentiate them from desktop computers where you can actually plug graphic cards and Ram.