It's because acetaminophen is extremely hepatotoxic at levels not very far above the recommended dosages.
> Hepatic injury and subsequent hepatic failure due to both intentional and non-intentional overdose of acetaminophen (APAP) has affected patients for decades, and [...] remains a global issue; in the United States, in particular, it accounts for more than 50% of overdose-related acute liver failure and approximately 20% of the liver transplant cases.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913076/
I would assert that acetaminophen is far more likely to be dangerous to far more children than puberty blockers and yet I don't see any moral panic over children's Tylenol.