Yes: ease of use, lots of additional power (for starters, you can modify traffic, not just view it) and being able to intercept anything (multiple tabs, multiple browsers, mobile, docker, CLI tools, backend services, you name) all in the same interface.

For the web dev case, for example, if you're debugging some interaction that means you can intercept your browser <-> server traffic and your server <-> upstream API traffic all in the same place, and see the full flow, and you can modify server responses or backend API responses in flight, to test out different edge cases.

There's a Chrome dev tools vs HTTP Toolkit comparison page here with a little more detail: https://httptoolkit.com/chrome-devtools-alternative/