in Azure that's roughly 5k per year if you pay for the whole year upfront.
I have the pleasure of playing with 64cores, 256gb RAM and 2xV100 for data science projects every now and then. That turns out to be roughly 32k per year.
--edit--
I forgot to add the following: that's 32k if you run the system 24/7. Usually it's up for a few hours per month, so you end up paying maybe 2k for the whole year.