A friend of mine got infected with prions. Well, it’s what the doctors believe since all other tests came up negative. They aren’t 100% sure but have documented it as that.
It’s amazing how quickly he degenerated. He was feeling weird physically and mentally and went to a doctor. Within a few months he was a different person but could recognize friends. He needed assistance for living. Within a year he was completely mentally gone. Just a different person with no means of communicating or doing anything for himself. Just completely sad.