The discussion here seems to have ignored what seems like the interesting/new part of this. There has been plenty of prior research and media around blanket use of antibiotics creating _drug resistant_ bacteria which are harder to fight with drugs. But this is saying that additionally because some antibiotics are similar to chemicals endogenously produced within our own bodies, they also produce bacteria which our bodies are less effective at fighting on their own.

I.e. this isn't just about the use of antibiotics -- this is about the use of antibiotics which are _similar to parts of our own immune systems_. Using antibiotics which are more dissimilar to our own immune responses would create _drug resistant_ bacteria but not _immune resistant_ bacteria.