Mostly academia and nation states. Physical access will always be king and this provides one more avenue for adversaries to bypass encryption more easily.
No. Your wording suggests that once attackers gain physical access, all is lost. It is not true. With a passphrase based full disk encryption, if the passphrase is strong and the machine is powered off, physical access doesn't imply data access.
https://www.bloomberg.com/news/features/2018-10-04/the-big-h...
This is _trivial_ for any mildly sophisticated attacker.
Room bugged = keyboard keylogged