Lobbyists would be hurt by term limits. The big winners would be the permanent bureaucracy, who are already more-or-less in charge. The real solution is to allow old school purges when parties trade control of government.
With AI getting better and better at processing natural language, I suspect one could automate a huge portion of what the civil service does and thereby make it easier for a political newcomer to replace the relatively smaller number of people managing the machines. Not sure how we'd get there though.