High fructose corn syrup is a very poor example. It is composed of fructose and glucose, both very familiar molecules to our bodies.
Now you can get sugary cereal for breakfast, sandwich bread with HFCS for your lunchtime sammo, and a curry jam packed with palm oil and sugar for dinner. And that doesn't count the cookies or Pepsi you slam in between.
Raw sugar of HFCS -- don't matter none, it's that you're slamming em at each meal, all the time.