Hopefully these ones will be tested longer than the last batch of mRNA designs, so that risks like the doubling of retinal vascular occlusion risk are identified before they go into production: https://www.nature.com/articles/s41541-023-00661-7
Based on the official COVID-19 death reports, it is estimated that vaccinations have prevented 14.4 million excess COVID-19 deaths worldwide between December 2020 and December 202139. Thus, vaccination is the most effective method for preventing the spread of SARS-CoV-2.
The number of reported ophthalmic complications has remained low, and vaccine-related retinal vascular occlusion is very rare, although the number of COVID-19 vaccinations is enormous.
Note that there was an attempted discussion of that paper on HN but it was immediately flagged to death. It always happens for every such paper. People still aren't ready to do a full and honest accounting. Probably they never will be.
Personally, I already spent two years dealing with physical threats and violence from antimask/antivax crazies, I'm not about to give them the time of day when they crawl out of the woodwork on the internet.
I said people flag stories that are research papers. As in, published by doctors. Not comments, not conspiracies, just collected data. Doesn't matter. People (like you?) flag them anyway to try and keep everyone else at the same intellectual darkness.