Deno has already been seeing increasing support for Node's API and built-ins... this means, they are now also available for running in Deno Deploy (cloud environment)... if you were using something where you deployed your own Deno (docker, etc) then you could already to this.
Note: Cloudflare Workers is also starting to support a lot of Node APIs as well (opt-in), so bundles will likely be able to run in both of them and others. Can't speak specifically to it, but Bun will probably also largely work.