For example looking for populations that aren't leaving houses.
It's a far-fetched scenario, but I don't know enough about the breakdown of DNA in wastewater to know if it'd be possible to locate him via this method. If he wasn't shedding a unique strain of a virus, let's say, but where his genetics are known.
This researcher explained to a reporter how they conducted a binary search of sewer lines from the treatment plant, all the way back to a single manhole which was only fed by a single employer with 30 employees. I just don't know if this is only possible using viral RNA, or if anyone's DNA would be possible to search on in a similar manner. For good public health reasons, we're likely to have continual wastewater surveillance at all major plants going forward - I just don't know how far it could be pushed.