Changing can work. If you scroll back to the start of a lot of popular providers and you'll find the originally produced very different stuff.
Even established channels can change. Eg JillBearup[1] used to post videos about science fiction, fantasy, movies. About 8 years in she started a new hobby and posted a few videos about stage fighting that were popular and then pivoted to costumes and fighting in movies. Roughly 10x jump in views per video.