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What I wonder: do they always align in the same body orientation, or is that just for the benefits of the cameras?

That's an interesting question. I wonder if it's not also social habit as it would be somewhat awkward to try to talk to someone's feet or if they were sideways to you.

During shared meals I suspect they do. It'd be awkward to hang out with an upside-down person.

So it seems, but perhaps after a while they would get used to it and new constellations could evolve :-)

Likewise I wonder if the ISS was designed with specific sides for up and down in mind of if all sides are created equal. In the video some signs are visible which seem to be all aligned in the same direction, but what about tools and furniture?

There are different sections. Most is pragmatic, but the crew areas have a "down" to make the people feel better when they stay there.

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